Tel. +34 913303000 (Ext. 482454)
Hospital Clínico San Carlos.
C/ Profesor Martín Lagos s/n. 28040 Madrid
Our group’s main line of research is the study of the involvement of environmental factors in the aetiopathogenesis of degenerative diseases and their possible use as biomarkers in the prognosis of the disease and in the response to treatment, as well as the study of the mechanisms of interaction between these environmental factors and the possible genetic factors of susceptibility to suffer from these diseases. In 1997 we began a new line of pioneering research in Spain: the study of the possible involvement of herpesviruses in the aetiopathogenesis of multiple sclerosis; we now have internationally validated detection protocols, have established multiple national and international collaborations, and have developed various projects that have been continuously funded both publicly (FIS) and privately, which has allowed us to publish more than 40 international articles on this particular subject. Recent years have also included the study of other environmental factors, such as JC virus, vitamin D, the study of human endogenous retroviruses (HERVs) and different metabolites of the microbiota, in this and other degenerative diseases. Finally, throughout this time, studies have also been carried out on the interaction between the different genetic susceptibility factors and the environmental factors studied, in order to study in depth, the possible mechanisms involved in the origin of these diseases.
Roberto Álvarez Lafuente has a Licentiate degree in Biology (UCM, 1994), a Licentiate degree in Biochemistry (UCM, 1999), and a PhD in Biology (Medical Microbiology Programme. UCM. 2000).
Principal Investigator of the Environmental Factors in Degenerative Diseases research group at the Health Research Institute (Instituto de Investigación Sanitaria) of the Hospital Clínico San Carlos.
He has participated as a researcher in Health Research Projects of the Instituto de Salud Carlos III since 1998 (as PI since 2013) and in the Spanish Multiple Sclerosis Network (REEM) in different calls since its creation (2008, 2013 and 2017); he is currently part of the new Inflammatory Diseases Network within the Networks of Cooperative Research Oriented to Health Outcomes (RICORS).
Collaborating researcher of a European project (H2020-JTI-IMI2-2018-14, Nº.831434) and principal investigator of projects in competitive calls funded by different private foundations (Ramón Areces, Mutua Madrileña, Esclerosis Múltiple España, LAIR, HHV-6 Foundation, etc.). Since 2009 he has supervised 7 doctoral theses.